Transposable elements (TEs) are mobile DNA sequences once referred to as "selfish DNA". While they have contributed significantly to genome evolution, their movement can often disrupt genes and lead to disease. To counteract this, organisms have developed post-transcriptional, transcriptional, and epigenetic mechanisms to control TE activity. This book explores the complex interplay between mobile genetic elements and human health, providing a comprehensive overview of TE biology, their modes of action, and the strategies ...
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Transposable elements (TEs) are mobile DNA sequences once referred to as "selfish DNA". While they have contributed significantly to genome evolution, their movement can often disrupt genes and lead to disease. To counteract this, organisms have developed post-transcriptional, transcriptional, and epigenetic mechanisms to control TE activity. This book explores the complex interplay between mobile genetic elements and human health, providing a comprehensive overview of TE biology, their modes of action, and the strategies employed to suppress their movement, and offering valuable insights into potential therapeutic interventions targeting TE-related diseases. In particular, the book reviews how TEs affect gene expression and contribute to diseases such as cancer, neurodegenerative diseases, and inherited disorders. Other topics include TE polymorphisms, epigenetic control, co-opted functions, non-coding RNAs, and their roles in environmental stress and immune pathways. Providing a comprehensive reference on the subject, this book is intended for researchers and advanced students in genetics and related disciplines.
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Add this copy of Transposable Elements, Transcriptomics, and Diseases to cart. $160.74, new condition, Sold by Educational Media Centre rated 4.0 out of 5 stars, ships from New Delhi, DELHI, INDIA, published 2025 by Springer.
Add this copy of Transposable Elements, Transcriptomics, and Diseases to cart. $175.62, new condition, Sold by Educational Media Centre rated 4.0 out of 5 stars, ships from New Delhi, DELHI, INDIA, published 2025 by Springer.
Add this copy of Transposable Elements, Transcriptomics, and Diseases to cart. $179.11, new condition, Sold by Basi6 International rated 5.0 out of 5 stars, ships from Irving, TX, UNITED STATES, published 2025 by Springer.
