Randomized Phase II Cancer Clinical Trials

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In cancer research, a traditional phase II trial is designed as a single-arm trial that compares the experimental therapy to a historical control. This simple trial design has led to several adverse issues, including increased false positivity of phase II trial results and negative phase III trials. To rectify these problems, oncologists and biostatisticians have begun to use a randomized phase II trial that compares an experimental therapy with a prospective control therapy. Randomized Phase II Cancer Clinical Trials ...

Randomized Phase II Cancer Clinical Trials 2013, CRC Press

ISBN-13: 9781439871850

Hardcover

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