Protein Tyrosine Kinases: From Inhibitors to Useful Drugs

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Leading researchers, from the Novartis group that pioneered Gleevec/Glivec (TM) and around the world, comprehensively survey the state of the art in the drug discovery processes (bio- and chemoinformatics, structural biology, profiling, generation of resistance, etc.) aimed at generating PTK inhibitors for the treatment of various diseases, including cancer. Highlights include a discussion of the rationale and the progress made towards generating "selective" low molecular-weight kinase inhibitors; an analysis of the normal ...

Protein Tyrosine Kinases: From Inhibitors to Useful Drugs 2010, Humana Press Inc., Totowa, NJ

ISBN-13: 9781617375347

Paperback

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Protein Tyrosine Kinases: From Inhibitors to Useful Drugs 2005, Humana Press

ISBN-13: 9781588293848

2006 edition

Hardcover

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