Optimizing the "Drug-Like" Properties of Leads in Drug Discovery

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Traditionally, incorporating optimal drug-like properties into a structural lead was not considered by medicinal chemists to be their responsibility. Instead, medicinal chemists felt that the undesirable drug-like properties in their drug candidates would be fixed by preclinical development scientists. However, that view has changed in the past 5b"10 years, resulting in another significant paradigm shift in drug discovery. The most significant aspect of this latest paradigm shift is the recognition by medicinal chemists ...

Optimizing the "Drug-Like" Properties of Leads in Drug Discovery 2016, Springer

ISBN-13: 9781493950478

Softcover Reprint of the Origi edition

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Optimizing the "Drug-Like" Properties of Leads in Drug Discovery 2006, Springer, New York, NY

ISBN-13: 9780387340562

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