Metallothioneins in Biochemistry and Pathology


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Metallothioneins (MTs) represent a large family of proteins characterized by high heavy metal content (mainly CuII and ZnII) and by an unusual cysteine abundance. They have a powerful protective function in all animal tissues, due most likely to their properties as free radical scavengers protecting against oxidative damage. Moreover, the presence and overexpression of MTs in various pathological conditions, such as metal dyshomeostasis, cell proliferation, neurological disorders, and chemotherapy and radiotherapy ...

Metallothioneins in Biochemistry and Pathology 2008, World Scientific Publishing Company, Singapore

ISBN-13: 9789812778932