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Handbook of Transcription Factor Nf-Kappab

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Recent evidence proving the molecular link between unchecked, chronic inflammation and cancer has implicated the transcription factor NF-kB as a key factor in both inhibiting apoptosis and promoting cell proliferation. Since its initial identification 20 years ago as a simple regulating factor in one small part of the immune response, NF-kB is proving to be the most protean of all transcription factors. It has been shown to function in most cell types as a key regulator of a number of inducible genes. Research on the ...

Handbook of Transcription Factor NF-kappaB 2006, CRC Press, Boca Raton, FL

ISBN-13: 9780849327940

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