Gene Therapy: Potential Applications of Nanotechnology


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Gene therapy is emerging as a new class of therapeutics for the treatment of inherited and acquired diseases. However, poor cellular uptake and instability of DNA in the physiological milieu limits its therapeutic potential, hence a vector which can protect and efficiently transport DNA to the target cells must be developed. Nanotechnology-based non-viral vectors have been proposed as potential candidates. Various polymeric nanoparticles have been shown to be suitable, with high cellular uptake efficiencies and reduced ...

Gene therapy: Potential Applications of Nanotechnology 2013, Woodhead Publishing Ltd, Cambridge

ISBN-13: 9781907568404