Gene Targeting: A Practical Approach

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The book begins by describing in detail the rationale behind designing gene targeting vectors, including both basic replacement vectors for creating null mutations and more sophisticated two-step approaches for creating subtle mutations. It describes the latest techniques for culturing and manipulating ES cells and a number of approaches for identifying rare targeted cell clones. Techniques for culturing and assaying for mouse and human hematopoietic progenitors in vitro and in vivo are then covered, followed by the design ...

Gene Targeting: A Practical Approach 2000, Oxford University Press, USA, Oxford, England

ISBN-13: 9780199637928

2nd edition

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Gene Targeting: A Practical Approach 1993, Oxford University Press, USA, Oxford, England

ISBN-13: 9780199634064

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Gene Targeting: A Practical Approach 1993, Oxford University Press, USA, Oxford, England

ISBN-13: 9780199634071

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