Filaggrin: Basic Science, Epidemiology, Clinical Aspects and Management

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Filaggrin gene mutations are common in Europeans and their descendants, as well as in Asians, reaching a prevalence of up to 10%. Filaggrin proteins are crucial for skin homeostasis as their metabolites maintain skin hydration, keep the skin pH low, and provide protection against solar radiation. FLG mutation carriers suffer from dry and scaly skin and have an increased transfer of allergens and chemicals across the epidermis. Moreover, they have 10% higher serum vitamin D levels, potentially affecting the propensity to ...

Filaggrin: Basic Science, Epidemiology, Clinical Aspects and Management 2016, Springer

ISBN-13: 9783662511176

Softcover Reprint of the Origi edition

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Filaggrin: Basic Science, Epidemiology, Clinical Aspects and Management 2014, Springer

ISBN-13: 9783642543784

2014 edition

Hardcover

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