Leading experts summarize and synthesize the latest discoveries concerning the changes that occur in tumor cells as they develop resistance to anticancer drugs, and suggest new approaches to preventing and overcoming it. The authors review physiological resistance based upon tumor architecture, cellular resistance based on drug transport, epigenetic changes that neutralize or bypass drug cytotoxicity, and genetic changes that alter drug target molecules by decreasing or eliminating drug binding and efficacy. Highlights ...

Cancer Drug Resistance 2010, Humana Press Inc., Totowa, NJ

ISBN-13: 9781617376221

Paperback

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Cancer Drug Resistance 2006, Humana Press

ISBN-13: 9781588295309

Hardcover

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