Alternative Mechanisms of Multidrug Resistance in Cancer

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Drug resistance, whatever its source, is the prevalent cause for treatment failure in cancer chemotherapy. At present, the best understood (and most publicized) mechanism of cell resistance is the P-glycoprotein mediated efflux pump. However, it is not the only - or even the most effective - tool of survival devices to be considered in this book. Alterations of topoisomerases and conjugases, glutathione transferases, protein kinase C, the multidrug resistance protein MRP, bc12 and other modes of action are considered as ...

Alternative Mechanisms of Multidrug Resistance in Cancer 2012, Birkhauser

ISBN-13: 9781461598541

Softcover Reprint of the Origi edition

Trade paperback

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Alternative Mechanisms of Multidrug Resistance in Cancer 1994, Birkhauser, Boston, MA

ISBN-13: 9780817637750

1995 edition

Hardcover

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