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Human Drug Metabolism: An Introduction

Human Drug Metabolism: An Introduction more books like this

by Michael Coleman

Drug metabolism is a core area of pharmacology. Before any drug can be licensed it is essential to know how the body metabolises the drug, and the short and long--term effects it has on the body. It is an area of rapid advancement, which brings together the fields of pharmacy, pharmacology and medicine. This new text provides a concise, user- ...

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Dangerous Pollutants (Xenobiotics) in Urban Water Cycle

Dangerous Pollutants (Xenobiotics) in Urban Water Cycle more books like this

by Ongjen Bonacci (Editor), Jiri Marsalek (Editor), Ivana Mahrikova (Editor)

The topics focused on evaluation of impact of xenobiotics in the whole Urban Water Cycle are an interdisciplinary task which has a rising concern these days. Xenobiotics includes both inorganic elements like heavy metals, metalloids and man-made organic compounds such as pesticides, surfactants, solvents, fragrances, flavors, and pharmaceuticals ...

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Principles of Biochemical Toxicology

Principles of Biochemical Toxicology more books like this

by John A Timbrell

Leading textbook in biochemical toxicology. Addresses dose-response relationships; metabolism; toxic responses, and provides detailed examples to illustrate mechanisms of toxicity.

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Mechanistic Toxicology: The Molecular Basis of How Chemicals Disrupt Biological Targets

Mechanistic Toxicology: The Molecular Basis of How Chemicals Disrupt Biological Targets more books like this

by Urs A Boelsterli

A thorough understanding of cellular and molecular mechanisms involved in the individual expression of toxic effects provides an important tool for assessment of human health risk. New aspects, major advances, and new areas in molecular and cellular biology and toxicology demand updated sources of information to elucidate the functional mechanics ...

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Disposition of Toxic Drugs and Chemicals in Man more books like this

by Randall C Baselt

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Microbial Transformations of Bioactive Compounds more books like this

by Rosazza

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Cytochromes P450: Metabolic & Toxicological Aspects more books like this

by Costas Ioannides (Editor)

Cytochromes P450: Metabolic and Toxicological Aspects examines cytochrome P450 proteins and their role in toxicity/carcinogenicity and the metabolism of foreign chemicals. Studying the function of these proteins enables us to:oPredict the pathways and outcome of chemical metabolism to rationalize species, sex, and age differences in ...

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T Lymphocytes Subpopulations in Immunotoxicology

T Lymphocytes Subpopulations in Immunotoxicology more books like this

by Maryjane K Selgrade (Editor), Ian Kimber (Editor), Mary Jane Selgrade (Editor)

T Lymphocyte Subpopulations in Immunotoxicology Edited by Ian Kimber ZENECA Pharmaceuticals, Central Toxicology Laboratory, Macclesfield, Cheshire, UK and Mary Jane K. Selgrade US Environmental Protection Agency, National Health and Environmental Effects Research Laboratory, NC, USA Immunotoxicology is a diverse discipline that embraces the ...

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Cytochromes P450: Role in the Metabolism and Toxicity of Drugs and Other Xenobiotics

Cytochromes P450: Role in the Metabolism and Toxicity of Drugs and Other Xenobiotics more books like this

by Costas Ioannides (Editor)

This up-to-date book provides the latest information on the cytochrome P450 enzymes, (one of the most extensively studied enzyme systems worldwide) in a very accessible manner. It deals extensively with each family/subfamily of the cytochromes P450 that contribute to the metabolism of xenobiotics. Essential and invaluable information is provided ...

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Environmental Toxicology more books like this

by John H Duffus

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Inhaled Xenobiotics

Inhaled Xenobiotics more books like this

by Bob Myers, Mill

This guide is designed for anyone filling the parental role - either temporarily or permanently. It explains how to maintain, repair and strengthen relationships with teenagers. Myers encourages adults to take control of the parenting situation by taking control of their own actions and reactions. He seeks to remove conflict from parent-child ...

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Xenobiotic conjugation chemistry more books like this

by Paulson, International Society for the Study of Xenobiotics, American Chemical Society Meeting, American Chemical Society Division of Pesticide Chemistry

Highlights advances in the understanding of the biosynthesis of xenobiotic conjugates in mammals, fish, insects, and plants. Describes current methods for the isolation and identification of xenobiotic conjugates. Provides evidence for and implications of newly discovered novel xenobiotic conjugates and the biological significance and consequences ...

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Nutritional Toxicology more books like this

by Frank N Kotsonis

This volume examines the relationship between the diet and the body's response to toxicants and presents scientific issues surrounding the safety and nutritional impact of new food technologies, novel foods, and new food ingredients. Topics discussed include the role of antioxidant nutrients in protection against free radicals, the influence of ...

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On-Site Bioreclamation: Processes for Xenobiotic and Hydrocaron Treatment more books like this

by Dr. Robert E Hinchee

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Xenobiotics in Fish

Xenobiotics in Fish more books like this

by David J Smith, M.D, William H Gingerich (Editor), Maria G Beconi-Barker (Editor)

Aquaculture is rapidly becoming a major source of fish protein used to meet the nutritional needs of humans. As the aquaculture industry grows, exposure of farmed fish to environmental contaminants, and the need for chemical therapeutic agents for fish, will increase. This book is designed to bring together authorities worldwide on the regulation ...

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N-Oxidation of Drugs

N-Oxidation of Drugs more books like this

by P Hlavica, L a Damani

The extensive use of nitrogen-containing compounds as pharmaceuticals and chemical intermediates can lead to exposure to a large number of these agents under widely varying conditions. Before elimination the xenobiotics usually undergo biotransformation. Oxidative attack at nitrogen centres can affect detoxification, but equally well can induce ...

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Clinical Immunotoxicology more books like this

by Newcombe S Newcombe, David S Newcombe (Editor)

This text is a comprehensive source of information on the toxic effects of environmental, industrial, and pharmacological agents on the human immune system. Focusing entirely on human immunotoxicology, without relying on animal models, the book explains the basic principles of immunotoxicology defines the mechanisms by which immunotoxins act, ...

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New Microbiotests for Routine Toxicity Screening and Biomonitoring

New Microbiotests for Routine Toxicity Screening and Biomonitoring more books like this

by Guido Persoone (Editor), Colin Janssen, Wim De Coen

These papers are from the "International Symposium on New Microbiotests for Routine Toxicity Screening and Biomonitoring - Development - Applications - Cost-effectiveness" which was organized in June 1998 in Brno, Czech Republic. It comprises 60 original and peer-reviewed papers selected from over 100 oral and poster presentations given during ...

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Xenobiotic Metabolism and Disposition: The Design of Studies on Novel Compounds more books like this

by Harry P a Illing, Illing P a Illing, H Ed Illing

This publication explains the principles of the techniques used in disposition and metabolism studies in animals, in man, and in vitro. It includes methods for studying routes and rates of absorption, distribution, metabolism, and excretion of novel compounds and their metabolites. Relevant surgical, whole-body autoradiographic and pharmacokinetic ...

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Xenobiosis more books like this

by Adrien Albert

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Xenobiotics and Food-Producing Animals: Metabolism and Residues more books like this

by David H Hutson (Editor), C B Struble (Editor), D R Hawkins (Editor)

Discusses the metabolism and fate of xenobiotic compounds, such as veterinary drugs, agrochemicals, and other products to which food-producing animals are exposed. Describes state-of-the-art techniques for experimental studies of xenobiotic compounds in ruminants, poultry, and aquatic species, including study design to meet specific regulatory ...

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Bioavailability of Organic Xenobiotics in the Environment more books like this

by P Baveye (Editor), J -C Block (Editor), V V Goncharuk (Editor)

In the continuing fight against organic environmental xenobiotics, the initial success attributed to bioremediation has paled, in part due to the low availability of xenobiotics entrapped within a soil or sediment matrix. This has generated a very significant wave of interest in the bioavailability issue. However, much experimental evidence is ...

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Physiologically Based Pharmacokinetic Modeling: Science and Applications more books like this

by Micaela B Reddy, Melvin E Andersen, PH.D., Raymond S H Yang, PH.D.

This book offers a definitive, single source of information on PBPK modeling. Physiologically-based pharmacokinetic (PBPK) modeling is becoming increasingly important in human health risk assessments and in supporting pharmacodynamic modeling for toxic responses. Organized by classes of compounds and modeling purposes so users can quickly access ...

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Hepatic Metabolism and Disposition of Endo- And Xenobiotics more books like this

by Karl-Walter Bock (Editor), W Gerok (Editor), S Matern (Editor)

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Plant Contamination: Modeling and Simulation of Organic Chemical Processes more books like this

by Stefan Trapp, MC Farlane MC Farlane, Craig MC Farlane

This book describes the physiological and anatomical principles and the chemical and physical factors that determine uptake, translocation, accumulation, loss, and metabolism of anthropogenic chemicals in plants. Expert authors in the fields of biology, chemistry, ecology, environmental physics, and biochemistry provide recently developed methods ...

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