Gene targeting a practical approach more books like this

by Joyner

Gene targeting is a relatively new area of research, and no comprehensive manual exists which specifically addresses producing mutant mice from embryonic stem cells. This book focuses on using gene targeting to produce mutant mice since this is the most popular and perhaps most powerful approach, however gene trap approaches and the use of ...

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Transgenics in Endocrinology more books like this

by Martin Matzuk, M.D. (Editor), Chester W Brown, M.D., Ph.D. (Editor), T Rajendra Kumar, Ph.D. (Editor)

A panel of expert clinical and basic investigators summarize the state-of-the-art in the use of transgenic technology in a broad range of endocrinological applications. Up-to-date and comprehensive, Transgenics in Endocrinology reviews the most recent developments in the analysis of endocrine physiology and its pathologies through mouse models, ...

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Cardiovascular Physiology in the Genetically Engineered Mouse more books like this

by Brian D Hoit (Editor), Richard A Walsh

The enormous advances in molecular biology and genetics coupled with the progress in instrumentation and surgical techniques have produced a voluminous and often bewildering quantity of data. The primary objective of a second edition of "Cardiovascular Physiology in the Genetically Engineered Mouse" is to interpret critically the literature and to ...

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new only from $137.07! | first editions | SVS

Overexpression and Knockout of Cytokines in Transgenic Mice more books like this

by Chaim O Jacob (Editor)

Cytokines are a steadily growing family of molecules which play a major role in intercellular communication. Key questions for the cytokine researcher today include 'which cytokines are involved in the pathophysiology of a disease or immune response', 'when do these cytokines function' and 'which of their many activities are relevant in vitro. The ...

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Mouse Genetics and Transgenics: A Practical Approach more books like this

by Ian J Jackson (Editor), Catherine M Abbott (Editor)

A unique book that integrates knowledge from a wide range of expertise, specifically applied to the mouse, and addressed at a wide audience from those new to the field to experts who want an update on the state of the art. Mouse Genetics and Transgenics: APA covers all aspects of using the mouse as a genetic model organism: care & husbandry; ...

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Transgenic and Knockout Models of Neuropsychiatric Disorders more books like this

by Gene S Fisch

In this up-to-date survey and critical assessment of transgenic and knockout models in neuropsychiatry and behavior, a panel of leading researchers comprehensively assesses how and whether the genetic abnormalities produced from these models manifest the neuropsychiatric disorders to which they correspond. The authors focus on transgenic and ...

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Gene Knockout Protocols more books like this

by Martin J Tymms (Editor), Ismail Kola (Editor)

Highly skilled investigators with extensive experience in gene targeting and mouse genetics describe their best techniques for the design of targeting constructs and for the analysis of the mouse phenotype. These include embryo transplantation, in vitro embryonic stem cell differentiation, creation of aggregation chimeras, mouse pathology, embryo ...

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Transgenic Models in Pharmacology more books like this

by Stefan Offermanns, Lutz Hein, M Bader

The aim of this volume is to give up-to-date information on animal models generated by transgenic or gene targeting techniques. Naturally, the focus is on the mouse system. Each chapter has been written by leading experts in the field and gives an overview on existing animal models. This is facilitated by tables, which list the most important ...

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new only from $386.00! | first editions

Genetically Engineered Mice Handbook more books like this

by John P Sundberg, D.V.M., Ph.D., Tsutomu Ichiki

While mice have always been highly popular laboratory subjects, their suitability for genetic engineering has solidified their position as today's lab animal model of choice. However, their increased use in genetic studies has created a demand for input on phenotyping that is not always easily met. To improve the flow of information on the ...

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Manipulating the Mouse Embryo: A Laboratory Manual more books like this

by Brigid Hogan

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Generation of Antibodies by Cell and Gene Immortalization more books like this

by Biotech 92

A major focus in current immunology research is on overcoming the problems that are encountered when antibodies raised in mice are used to treat human diseases such as cancers. Many of the various approaches to these problems are covered by contributions to this book: cloning of specific antibody fragments and antibody reshaping in bacteria and ...

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Transgenic Models in Endocrinology more books like this

by Maria G Castro

"Transgenic Models in Endocrinology" is a fitting addition to the "Endocrine Updates" series. The aim of these publications is to provide the clinician with cutting edge, yet succinct, access to the latest advances in endocrinology. Current advances in this rapidly evolving area of endocrinology make this a timely and important update for ...

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Manip the Mouse Embryo-3rd Ed (P) more books like this

by Andras Nagy, Marina Gersenstein, Kristina Vintersten

Regarded as the Bible of mammalian embryo manipulation techniques since the 1986 publication of the first edition of Manipulating the Mouse Embryo: A Laboratory Manual, the third edition of this essential laboratory resource has now been completely reorganized, rewritten, and updated by a new cast of authors. The result is a compilation of new, ...

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Manipulating the Mouse Embryo: A Laboratory Manual more books like this

by Andras Nagy, Marina Gertsenstein, Kristina Vintersten

This edition offers a compilation of contemporary protocols that include embryonic stem cell production and genetic manipulation, mouse chimeras, mouse cloning, assisted reproduction strategies (including intracytoplasmic sperm injection and in vitro fertilization), whole embryo culture systems, electroporation, embyro and gamete cryop-reservation ...

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Transgenic Mice and Mutants in Mhc Research more books like this

by I K Egorov

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Transgenic Mice as an in Vivo Model for Self Reactivity more books like this

by David A Ferrick

This work presents descriptions of transgenic models that address how the immune system copes with a genetically-engineered, self-reactive situation. Descriptions of the prototypic systems are provided, and the differences and nuances of related transgenic models are compared and contrasted.

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