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Killer Cell Dynamics: Mathematical and Computational Approaches to Immunology
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Dominik Wodarz
This book reviews how mathematics can be used in combination with biological data in order to improve understanding of how the immune system works. This is illustrated largely in the context of viral infections. Mathematical models allow scientists to capture complex biological interactions in a clear mathematical language and to follow them to ...
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T Lymphocytes Subpopulations in Immunotoxicology
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Maryjane K Selgrade (Editor), Ian Kimber (Editor), Mary Jane Selgrade (Editor)
T Lymphocyte Subpopulations in Immunotoxicology Edited by Ian Kimber ZENECA Pharmaceuticals, Central Toxicology Laboratory, Macclesfield, Cheshire, UK and Mary Jane K. Selgrade US Environmental Protection Agency, National Health and Environmental Effects Research Laboratory, NC, USA Immunotoxicology is a diverse discipline that embraces the ...
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T Cell Protocols: Development and Activation
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Kelly P Kearse (Editor)
Kelly P. Kearse and a panel of laboratory experts describe the step-by-step execution of a wide variety of basic and specialized techniques for the study of T cell developmental biology and of their subsequent activation. Readily reproducible, the techniques are explained concisely, but in such detail that they are suitable for both the novice and ...
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Cell Death During HIV Infection
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Andrew D Badley (Editor)
Although immune-based therapies have been the primary focus in the battle to arrest HIV, researchers now are considering the implications of apoptosis dysregulation during HIV-induced immunodeficiency. Mounting evidence indicates that cell death is not a passive process, but rather one that is tightly coordinated and regulated. This opens the door ...
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The Molecular Biology of B-Cell and T-Cell Development
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John Gordon Monroe (Editor), Ellen Rothenberg (Editor)
This cutting-edge review of the current status of research on the early development of lymphocytes emphasizes molecular mechanisms controlling lineage commitment and selection. The reviews explore cellular and molecular aspects of the microenvironment in regulating lymphoid development, discuss ligands and receptors that mediate interactions ...
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T Cell Receptors
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Owen Simpson Bell, Elizabeth Simpson (Editor), Michael J Owen (Editor)
T cell receptors covers biochemical, functional and genetic aspects of this key family of immunological molecules. It should be essential reading for all those interested in the TCR and its function in health and disease. It deals with the TCR protein, its functional interactions with the signal transduction machinery of the T cell and with the ...
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The T Cell Receptor FactsBook
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Marie-Paule Lefranc, Gerard Lefranc
The T Cell Receptor FactsBook contains entries on all the 176 functional variable, diversity, joining, and constant regions of the human T cell receptor, including alpha, beta, gamma, and delta loci. Introductory chapters summarize information of T cell receptor chain synthesis, chromosomal location, and an overview of the human T cell receptor ...
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Generation and Effector Functions of Regulatory Lymphocytes
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Novartis Foundation Symposium (Creator)
Over the last several years, immunologists have re-discovered the importance of regulatory lymphocytes, formerly termed 'suppressor cells'. Many recent reports have documented their existence, effector functions and potential therapeutic benefits in autoimmunity and transplantation. However, even though modern techniques have allowed us to get a ...
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Immune networks
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Constantin A. Bona, Heinz Köhler
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T Lymphocytes
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I Nicholas Crispe (Editor)
T Lymphocytes in the Liver is the first book to offer a comprehensive review of the newly understood relationship between the liver and the immune system. This edited volume examines the immunobiology of T cells - the way their behavior in the liver differs from that in other organs, and, conversely, the liver's ability to effect changes in the ...
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T Cell Hybridoas
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Michael J Taussig
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Lymphocyte Homing to the Skin
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by
Wolf-Henning Boehncke (Editor)
Over the last decade, enormous progress in the understanding of T-cell homing has made it possible to identify the multitude of molecules involved, such as cytokines, chemokines, and adhesion molecules, and to unravel their complex interactions resulting in controlled, non-random T-cell recirculation. These insights are now being explored ...
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Limiting dilution analysis of cells in the immune system
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by
Ivan Lefkovits, Ivan Leftovits, Herman Waldman
The second edition retains the same overall structure of the first edition, with one important addition - an extensive LDA software package. Useful to a broader audience in microbiology, pathology, virology and cellular biology.
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Multichain Immune Recognition Receptor Signaling: From Spatiotemporal Organization to Human Disease
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by
Alexander Sigalov (Editor)
Multichain Immune Recognition Receptors (MIRRs) represent a family of surface receptors expressed on different cells of the hematopoetic system and function to transduce signals leading to a variety of biologic responses. These receptors share common structural features, including extracellular ligand-binding domains and intracellular signaling ...
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Compilation Techniques for Reconfigurable Architectures
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Joao M P Cardoso (Editor), Pedro C Diniz (Editor)
This book describes a wide range of code transformations and mapping techniques for compiling programs written in high-level programming languages to reconfigurable architectures. While many of these transformations and mapping techniques have been developed in the context of compilation for traditional architectures and high-level synthesis, ...
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Analyzing T Cell Responses: How to Analyze Cellular Immune Responses Against Tumor Associated Antigens
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Dirk Nagorsen (Editor), F M Marincola (Editor)
This book reviews, describes, categorizes and provides a critical assessment of all assays that have been used for the monitoring of antigen-specific immune responses. In particular, it emphasizes a global approach to the analysis of T cell mediated target/host interactions at the systemic and the peripheral level when such interactions are ...
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T-Cell Vaccination
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by
Jingwu Zhang
This book provides a comprehensive review of T cell vaccination which is a topic of significant interest in the field of Immunology. However, its academic value is not limited to basic research into the understanding of autoimmune T cell regulation in vivo, for the research is supported by preliminary clinical application. Indeed, T cell ...
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T-Cell Receptors
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Tak W Mak (Editor)
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Mucosal T Cells
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by
Thomas T MacDonald (Editor)
The aim of this book is to cover all the important aspects of the biology of gastrointestinal and lung T cells in animals and in man. Basic observations are described as well as disease states where aberrant activation of mucosal T cells causes tissue damage.
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Intrathymic T-Cell Development
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by
Janko Nikolic-Zugic
This text describes and interprets current advances in the field of thymology and provides a comprehensive review of the literature. The author's personal views and hypotheses on unresolved issues of T cell development are presented throughout the text. Chapters cover the biology of thymic epithelium, thymocte development and the role of CD8 and ...
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Role of the Thymus in Tolerance Induction
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by
Marion Kendall
The first part of the book is an in-depth review into the events which lead to the production of functioning T cells. The second part of the book includes a close and detailed look at thymocyte differentiation and thymic microenvironment in the fetal rat thymus.
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Handbook of B and T Lymphocytes
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by
E Charles Snow (Editor)
Provides a broad overview of the historical and current research in B- and T-cell biology and presents the latest developments in this field for all professionals concerned with the humoral immune response of the body.
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Biology of the Chemokine Rantes
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Human B Cell Populations
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by
M Ferrarini
B cells used to be considered as a homogeneous population of cells destined to produce antibodies of increasing affinity and to maintain an immunological memory. In recent years, it has been determined that B cells can be subdivided into different subsets characterized by distinct morphologic, phenotypic and functional features. Presenting results ...
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Immunotherapy of Cancer with Sensitized T Lymphocytes
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by
Alfred E Chang
This text is a review of the field of cellular immunotherapy utilizing sensitized T lymphocytes. The contributors are experts in the field of experimental and clinical immunotherapy. Cellular therapy of malignancy has become more feasible with an increased understanding of the interactions between immune cells and tumours. The text reviews the ...
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