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Immunological Tolerance: Methods and Protocols
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Paul J Fairchild (Editor)
"Immunological Tolerance: Methods and Protocols" is a comprehensive guide to the techniques currently used for culturing and characterising the cell types responsible for imposing self-tolerance and the experimental models employed to study their function both in vitro and in vivo.
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T Lymphocytes Subpopulations in Immunotoxicology
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Maryjane K Selgrade (Editor), Ian Kimber (Editor), Mary Jane Selgrade (Editor)
T Lymphocyte Subpopulations in Immunotoxicology Edited by Ian Kimber ZENECA Pharmaceuticals, Central Toxicology Laboratory, Macclesfield, Cheshire, UK and Mary Jane K. Selgrade US Environmental Protection Agency, National Health and Environmental Effects Research Laboratory, NC, USA Immunotoxicology is a diverse discipline that embraces the ...
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T Cell Protocols: Development and Activation
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Kelly P Kearse (Editor)
Kelly P. Kearse and a panel of laboratory experts describe the step-by-step execution of a wide variety of basic and specialized techniques for the study of T cell developmental biology and of their subsequent activation. Readily reproducible, the techniques are explained concisely, but in such detail that they are suitable for both the novice and ...
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Limiting Dilution Analysis of Cells of the Immune System
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Ivan Lefkovits, Herman Waldmann, P Rovensky
This edition is a treatise on the rationale of limiting dilution analysis (LDA). LDA has evolved from its previous role as a basic research laboratory tool in virology and immunology to one pertaining to many different research disciplines and to clinical applications. New methodologies (such as PCR, confocal microscopy, in situ hybridization) ...
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Cytotoxic Cells: Recognition, Effector Function, Generation, and Methods
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Michail Sitkovsky, P a Henkart (Editor)
This collection of papers from researchers of cytotoxic cells provides a state-of-the-art review of this field. Special chapters cover the mechanisms of lethal hit delivery and immuno-pharmacological manipulations of cytotoxic cells.
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Natural Killer T-Cells: Roles, Interactions, and Interventions
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Nathan V Fournier
Natural killer T (NKT) cells are a heterogeneous group of T cells that share properties of both T cells and natural killer (NK) cells. Many of these cells recognize the non-polymorphic CD1d molecule, an antigen-presenting molecule that binds self and foreign lipids and glycolipids. Upon activation, NK T cells are able to produce large quantities ...
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Superantigens #7 (93)
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Brigitte T Huber, Brigitte T Huber (Editor), Ed Palmer (Editor)
Superantigens are microbial products that defy the conventional notion of lymphocyte activation to produce an unusually vigorous, genetically unrestricted response among many subsets of antigen-specific T cells. Bacterial toxins and certain viral gene products behave as superantigens, deleting T cells in vivo and stimulating their proliferation in ...
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T-cell-directed immunointervention
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by
Bach
Autoimmunity, the phenomenon by which the body's immune system attacks itself instead of invading organisms, is a factor in a wide range of currently
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Handbook of Elispot: Methods and Protocols
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Alexander E Kalyuzhny (Editor)
In this first book dedicated entirely to the ELISPOT, a critical enzyme-linked immunospot assay used widely in biomedical research, recognized experts with first-hand experience detail how to design, perform, and analyze these assays. The readily reproducible techniques they provide cover a wide variety of topics, including the use of membrane ...
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Compilation Techniques for Reconfigurable Architectures
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Joao M P Cardoso (Editor), Pedro C Diniz (Editor)
This book describes a wide range of code transformations and mapping techniques for compiling programs written in high-level programming languages to reconfigurable architectures. While many of these transformations and mapping techniques have been developed in the context of compilation for traditional architectures and high-level synthesis, ...
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Tumor Antigens Recognized by T Cells and Antibodies
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Kobena J Mercer, Hans J Stauss (Editor), Yutaka Kawakami (Editor)
Recent progress in fundamental tumor immunology has led to immunotherapy trials in patients with solid tumors and hematological malignancies. In the past, immunotherapy approaches were primarily based on enhancement of tumor immunity with cytokines and adjuvant therapy, without knowledge of relevant tumor antigens. The discovery of tumor antigens ...
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Mucosal T Cells
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Thomas T MacDonald (Editor)
The aim of this book is to cover all the important aspects of the biology of gastrointestinal and lung T cells in animals and in man. Basic observations are described as well as disease states where aberrant activation of mucosal T cells causes tissue damage.
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Advances in the Immunopathogenesis of Multiple Sclerosis
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Domencio Gambi (Editor), Allesandra Lugaresi (Editor), Paolo A Muraro (Editor)
This volume highlights recent advances in the basic mechanisms of the immunopathogenesis of multiple sclerosis. Written by scientists actively involved in leading research, it mainly focuses on aspects of autoreactive T cell activation. Progress in the field of blood-brain barrier damage pathophysiology, antigen presentation in the central nervous ...
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Interleukin 2
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Kendall A Smith
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Cytotoxic T cells : biology and relevance to disease
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Jack R. Battisto, Janet Plate, Gene M. Shearer, New York Academy of Sciences
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Phylogeny of Thymus and Bone Marrow--Bursa Cells: Proceedings of an International Symposium on the Phylogeny of T and B Cells, New Orleans, Louisiana,
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Richard Kenneth Wright
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Biology of the Chemokine Rantes
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Human B Cell Populations
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by
M Ferrarini
B cells used to be considered as a homogeneous population of cells destined to produce antibodies of increasing affinity and to maintain an immunological memory. In recent years, it has been determined that B cells can be subdivided into different subsets characterized by distinct morphologic, phenotypic and functional features. Presenting results ...
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Thymus: Regulator of Cellular Immunity
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by
John A Goss
Reviewing the role played by the thymus in the regulation of cellular immunity, this text discusses basic anatomy and physiology of the mammalian thymus, including reviews of thymic embryology, gross anatomy, microanatomy, microenvironment, and cytokines and hormones produced by the thymus. This knowledge is applied to clinical entities such as ...
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Immunotherapy of Cancer with Sensitized T Lymphocytes
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by
Alfred E Chang
This text is a review of the field of cellular immunotherapy utilizing sensitized T lymphocytes. The contributors are experts in the field of experimental and clinical immunotherapy. Cellular therapy of malignancy has become more feasible with an increased understanding of the interactions between immune cells and tumours. The text reviews the ...
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Basic Mechanisms of Physiologic and Aberrant Lymphoproliferation in the Skin
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Willem A Van Vloten (Editor), Benvenuto Giannotti (Editor), W C Lambert (Editor)
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T Cells in Arthritis
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Wim B Van Den Berg, Gary S Firestein, Pierre Miossec
Rheumatoid arthritis (RA) is the most common and most severe form of inflammatory arthritis. The pathogenesis of RA has been the subject of intense research for several decades. The prevailing hypotheses have changed over the years, and have attempted to incorporate the most recent data. Although T cells represent an important component of the ...
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Specificity Func Clon Dev T Cells
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Alan Fleischer, Jr., B Fleischer (Editor), J Reimann (Editor)
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Human T-cell lymphotropic virus type I
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Höllsberg, Hafler
HTLV is made up of any of several retroviruses including the retrovirus known as AIDS. Devoted to the rapidly growing field of HTLV, this book explores the many different aspects of the virus.
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Molecular Mechanisms of Immune Response
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W F Bodmer (Editor), M J Owen (Editor), Imperial Cancer Research Fund (Editor)
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