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Proteomics
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by
Timothy Palzkill
"Proteomics" is an introduction to the exciting new field of proteomics, an interdisciplinary science that includes biology, bioinformatics, and protein chemistry. The purpose of this book is to provide the active researcher with an overview of the types of questions being addressed in proteomics studies and the technologies used to address those ...
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Lymphocyte Signal Transduction
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by
Constantine Tsoukas (Editor), Ed Tsoukas Constantine
Signal transduction through leukocyte receptors involves a variety of signaling molecules including kinases, phosphatases, adaptor proteins, small GTPases GTP exchange factors, membrane phospholipids as well as others. These signal transducers, regulated by inter- and intra-molecular interactions, as well as by various post-translational ...
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Post-Translational Modifications of Proteins: Tools for Functional Proteomics
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by
Christoph Kannicht (Editor)
The majority of all proteins undergo co- and/or post-translational modifications, crucially altering physical and chemical properties, folding, conformation distribution, stability, activity, and, consequently, the function of the proteins. In Post-translational Modifications of Proteins: Tools for Functional Proteomics, Second Edition, this ...
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Sebs 53 Post-Transltn Modifcat
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N H Battey (Editor), H G Dickinson (Editor), A M Hetherington (Editor)
Post-translational modifications are now known to play a fundamental role in regulating the activity, location and function of a wide range of proteins. In plant cells work on different types of post-translational modifications has progressed largely along independent lines. This book brings research workers together to allow an exchange of ideas, ...
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Co- and post-translational modification of proteins chemical principles and biological effects
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by
Graves, Martin 1959-, Wang
This work presents the general biological principles--and the chemical and physical concepts-- needed for an understanding of the post- and co-translational modification of proteins, a fundamental topic in the science of protein biochemistry and molecular biology. Examples of the different types of modification reactions (glycosylation, ...
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Posttranslational Modifications of Proteins: Tools for Functional Proteomics
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by
Christoph Kannicht (Editor)
Christoph Kannicht and a panel of highly experienced researchers describe readily reproducible methods for detecting and analyzing the posttranslational modifications of protein, particularly with regard to protein function, proteome research, and the characterization of pharmaceutical proteins. Among the methods presented are those for analyzing ...
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Lipid Modifications of Proteins
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by
Schlesinger J Schlesinger, Milton J Schlesinger
This is the only comprehensive one-volume work describing protein-bound lipids. "Lipid Modifications of Proteins" is the first single-volume publication to provide a comprehensive discussion of the five major kinds of protein-bound lipids. The book examines the biochemical activities involved in covalent attachment of different kinds of lipids to ...
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Mechanisms of Intracellular Trafficking and Processing of Proproteins
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Y Peng Loh (Editor)
"Mechanisms of Intracellular Trafficking and Processing of ProProteins" provides an in-depth discussion of the cellular organization and current views of the molecular mechanisms underlying the trafficking, sorting, and processing of various classes of proproteins. The book covers the mechanisms of pro-protein translocation across the rough ...
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Lipid modifications of proteins
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by
Patrick J Casey (Editor), Janice E Buss (Editor)
General Description of the Volume: This volume presents the best techniques and strategies for the study of lipid modified proteins, with particular emphasis on methods which evaluate the functional significance or biological impact of lipid modification. Included are the biological methods for the study of function (yeast genetics; cloning ...
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Protein Lipidation Protocols
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by
Michael H Gelb (Editor)
An all-star collection of readily reproducible techniques for studying protein lipidation, the covalent attachment of lipids to proteins. These cutting-edge methods - many never published before in a "hands-on" format - deal with glycosyl phosphatidylinositol (GPI)-containing compounds, protein protein fatty acylation, and protein prenylation. ...
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Proteome Research: New Frontiers in Functional Genomics
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by
M R Wilkins
Advances in two-dimensional electrophoresis, protein microanalysis and bioinformants have made possible the large-scale, systematic analysis of proteins and their post-translational modifications from any tissue or organism. This approach has acquired the name of "proteome research", and can be considered as the core of functional genomics. The ...
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Cancer Epigenetics
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by
Trygve Tollefsbol (Editor)
During the past few decades, it has become increasingly apparent that heredity is not the sole determining factor in disease development, such as cancer. This landmark work covers a wide array of aspects in the relatively new area of epigenetics, ranging from its role in the basic mechanisms of tumorigenesis, to the newest epigenetic drugs being ...
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Lipid modification of proteins a practical approach
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by
Hooper, Turner 1947-
Recent developments have shown that proteins can undergo a diverse range of modifications by lipid which can dramatically effect their structural and functional properties. These modifications include acylation, isoprenylation, and the attachment of glycolipid. Lipid modifications of proteins play important roles in cellular signalling, protein ...
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Post-Transitional Processing: A Practical Approach
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by
Steven Higgins (Editor), David Hames (Editor), B D Hames (Editor)
Post - Translational Modification: A Practical Approach and its companion volume Protein Expression: A Practical Approach form the final part of the PAS mini-series on protein synthesis and processing. This volume begins with a chapter on protein sequencing followed by a chapter on protein folding and import into organelles. The next three ...
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Post-Translational Modifications of Proteins
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by
John J Harding, M James C Crabbe, Harding J Harding
"Post-Translational Modifications of Proteins" discusses several important topics of interest to researchers and students in protein chemistry and biochemistry, including the occurrence and function of hydroxylated residues and the three enzymes required for their formation; the damaging effects of reactions between sugars and proteins; ADP ...
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Posttranslational Modification of Proteins: Expanding Nature's Inventory
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by
Christopher T Walsh
The number of protein isoforms in proteomes can be two to three orders of magnitude higher than the number of genes in the genomes. This is in large part due to posttranslational modifications of proteins that provide covalent alterations to protein backbones and side chains that increase proteome complexities. Greater than 5% of the genes in the ...
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Posttranslational covalent modifications of proteins
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by
B Connor Johnson
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Post-Translational Processing: A Practical Approach
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by
Steven Higgins (Editor), David Hames (Editor), B D Hames (Editor)
This text and its companion volume "Protein Expression: A Practical Approach" form the final part of the PAS mini-series on protein synthesis and processing. This volume begins with a chapter on protein sequencing followed by a chapter on protein folding and import into organelles. The next three chapters cover the three major forms of covalent ...
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Advances in Post-Translational Modifications of Proteins & Aging
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by
Vincenzo Ed Zappia
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D-Amino Acids in Sequences of Secreted Peptides of Multicellular Organisms
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by
Pierre Jolles (Editor)
Life on Earth almost exclusively uses laevorotatory or left-hended amino acids, rather than D-enantiomers. However, with improved analytical methods, D-amino acids have been detected in a variety of peptides of milticellular organisms. This work takes stock of the present knowledge in this expanding field of research. It discusses the ...
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The Enzymology of Post-Translational Modification of Proteins
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R B Freedman
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Protein Synthesis
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Abraham K Abraham
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Tyrosine Phosphorylation/Dephosphorylation and Downstream Signalling
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by
L. M. G. Heilmeyer
Nearly every cellular activity, such as cell growth, proliferation, protein synthesis and nuclear division, is regulated by protein phosphorylation/dephosphorylation on tyrosine residues as initiation events. Synchronization occurs through the interaction of protein tyrosine kinases and phosphatases. This book unveils signal pathways that connect ...
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Post-Translational Modification of Proteins by Lipids: A Laboratory Manual
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U Brodbeck
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Cellular Regulation by Protein Phospholyation
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by
Ludwig Heilmeyer
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