In this volume new drugs are described in detail and the philosophy for developing and using new drug therapies is explained. Emphasis is placed on how newer drugs have changed the traditional treatment paradigm for specific diseases such as cardiovascular illness, respiratory disease and psychological disorders. The author reviews the reasons ...
The most up-to-date and practical text in the field, "Applied Clinical Pharmacokinetics" features clear, useful coverage of drug dosing and monitoring. It focuses on the latest standardized techniques and approaches to patient-specific dosing and provides the most current information on recently monitored drugs. Readers will find new sections on ...
"Basic Clinical Pharmacokinetics" was designed to simplify pharmacokinetics to help busy practitioners understand and visualize basic principles. An easy-to-read, case-study format has made the text a favorite among clinical professors, students, and practitioners. The text provides an introduction to the principles of monitoring drug therapy for ...
Since pharmacokinetics can greatly affect how different patients respond to the same drug, both students and physicians need a basic clinical understanding of this vital area. The Third Edition of "Clinical Pharmacokinetics" provides a practical perspective, with these added features considerations of both stereochemistry and the increasing number ...
This unique textbook provides an introductory, yet comprehensive overview of the pharmaceutical sciences. It is the first text of its kind to pursue an interdisciplinary approach in this area of study. Readers are introduced to basic concepts related to the specific disciplines in the pharmaceutical sciences, including pharmacology, pharmaceutics, ...
The most comprehensive text on the practical applications of biopharmaceuticals and pharmacokinetics! 4 Stsr Doody's Review! 'The updated edition provides the reader with a solid foundation in the basic principles of pharmacokinetics and biopharmaceutics. Students will be able to apply the information to their clinical practice and researchers ...
A book in pharmacology which finally distinctly meets the needs of the allied health professional. The focused teach-and-test approach of this book provides readers with the perfect blend of concise content and an enjoyable--even fun--learning process. Pharmacology and fun have never been joined in the same sentence--until now! Uniquely designed ...
This unique text helps students and healthcare professionals master the fundamentals of pharmacokinetics and pharmacodynamics. Written by distinguished international experts, it provides readers with an introduction to the basic principles underlying the establishment and individualization of dosage regimens and their optimal use in drug therapy. ...
A natural hierarchy exists in pharmacokinetic-pharmacodynamic modeling culminating in population pharmacokinetic models, which are a specific type of nonlinear mixed effects model. The purpose of this book is to present through theory and example how to develop pharmacokinetic models, both at an individual and population level. In order to do so, ...
Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that rationalize drug action and allow the reader to extrapolate to many related ...
The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. The book is divided into four parts; the first deals ...
The Third Edition of Applied Pharmacokinetics remains the gold standard by which all other clinical pharmacokinetics texts are measured. Written by leading pharmacokinetics researchers and practitioners, this book is the most advanced kinetics reference available. All chapters have been extensively updated or completely rewritten for this edition ...
Designed as a reference text, this book focuses on the basic science, pharmacokinetics and clinical pharmacology of the drugs commonly used in anaesthesiology. Tables are included which review several literature sources for pharmacokinetics parameters.
Thoroughly updated, this reference presents comprehensive coverage of perspectives of metabolism-based drug-drug interactions. It provides helpful examples, representative enzyme systems, and computer-aided modeling to clarify key concepts.
"Medicinal Chemistry: An Introduction, Second Edition" provides a comprehensive, balanced introduction to this evolving and multidisciplinary area of research. Building on the success of the First Edition, this edition has been completely revised and updated to include the latest developments in the field.Written in an accessible style, "Medicinal ...
This reference/text examines the importance of toxicokinetics on drug disposition and outlines its practical applications in drug development - helping readers incorporate the most up-to-date findings into their own work.;Consolidating research from international authorities in the fields of toxicology, pharmacokinetics, metabolism and ...
This volume provides an in-depth view on the current state of research and clinical application of intravenous anaesthesia. It is divided into three sections with subjects on pharmacokinetic and dynamic modelling of anaesthetic action, monitoring and clinical application of intravenous anaesthesia and on the determination and meaning of effect ...
Containing the latest findings on the toxicity of a wide range of chemotherapeutic agents, this up-to-the-minute reference offers expert analyses on the pharmacokinetic-pharmacodynamic and pharmacokinetic-toxicodynamic relationships of anticancer compounds. "Anticancer Drug Toxicity" explores therapeutic drug monitoring (TDM) as a method of ...
This text provides detailed information about how drugs interact with one another when treating patients with cancer. It is intended to aid in the design of treatment studies and therapeutic monitoring for cancer patients. The initial chapters address the tools for assessing pharmacokinetics and pharmacodynamic endpoints and the advantages and ...
Gerontokinetics: Pharmacokinetics of Drugs in the Elderly is concerned with the complex processes of how the body handles drugs. After dealing with changes in the anatomy and physiology of the human body with increasing age, the pharmacokinetics of drugs in the elderly is discussed. In particular, five processes are discussed: liberation, ...
Providing contributions drawn from experts' specialties of medicine, medical microbiology, pharmacology, therapeutics, medical oncology, infectious disease, biochemistry, molecular biology, and cell biology, this book explores drug transport and its role in resistance in antimicrobial and cancer chemotherapy. The book establishes the biochemical ...
The medical benefits of a drug are not only dependent on its biological effect, but also on its "life cycle" within the organism - from its absorption into the blood, distribution to tissue until its eventual breakdown or excretion by the liver and kidneys. Here, the authors, all of them employed at Pfizer in the discovery and development of new ...
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