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DNA Arrays
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Jang B Rampal (Editor)
Microarray technology provides a highly sensitive and precise technique for obtaining information from biological samples, with the added advantage that it can handle a large number of samples simultaneously that may be rapidly analyzed. The protocols collected in this important volume provide instruction in designing and constructing DNA arrays ...
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Chemistry of Nucleosides and Nucleotides
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LeRoy B Townsend
This third of four volumes continues the work of its well-received predecessors by providing comprehensive articles on specific lines of research. All volumes are written with medicinal chemists, organic chemists, physical chemists, and biological chemists in mind. Additionally, with the spate of recent research on the anticancer, antiviral, and ...
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The P2 Nucleotide Receptors
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John T Turner, Pro (Editor), Jeffrey S Fedan (Editor), Gary A Weisman (Editor)
A state-of-the-art summary from leading laboratories around the world of our current knowledge of the molecular biology, the physiology, and the pharmacology of the P2 receptors. The authoritative contributions cover the major aspects of these receptors, describing the relationships between physiological and pharmacological effects of ATP and ...
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Cyclic Nucleotide Phosphodiesterases in Health and Disease
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Joseph A Beavo (Editor), Sharron H Francis (Editor), Miles D Houslay (Editor)
Since the last major compendium dedicated to cyclic nucleotide phosphodiesterases (PDEs) was published over 15 years ago, an enormous amount of progress has occurred in the field. The number of identified PDEs has doubled, their roles in intracellular communication have begun to be understood, and several PDE inhibitors have entered the ...
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Hormone Action, Part A, Steroid Hormones: Volume 36: Hormone Action Part B
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Colowick, Bert W O'Malley (Editor), J G Hardman (Editor)
The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential ...
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Cyclic nucleotide phosphodiesterases structure, regulation and drug action
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Beavo, Houslay
Molecular Pharmacology of Cell Regulation Series Editor: M. D. Houslay This important Series provides topical, in depth and authoritative reviews on all aspects of the molecular mechanisms of cell regulatory processes. It attempts to unravel the molecular structures, properties and functions of systems which provide putative targets for the next ...
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Purines in Cellular Signalling: Targets for New Drugs
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Kenneth Alan Jacobson
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CRC Handbook of Nucleobase Complexes: Transition Metal Complexes of Naturally Occurring Nucleobases and Their Derivatives, Volume I
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James R Lusty, Suresh Garimella (Contributions by), Boyle (Contributions by)
The purpose of this easy-to-use handbook is to provide a quick, accessible reference to nucleobase complexes. It describes these complexes with reference to methods of preparation, their characterization, and their toxicity and therapeutic indices. It lists the modes of coordination together with the relevant spectral data and major methods of ...
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Nucleotide Analogues as Antiviral Agents
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John C Martin (Editor)
Largely in response to the AIDS epidemic, the amount of research directed toward the discovery of antiviral agents has greatly expanded. This new volume focuses on the potential of nucleotides to exert potent in vivo antiviral effects. It presents the findings of an international group of scientists who are carrying out research at the forefront ...
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Antisense Technology: A Practical Approach
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Nellen Lichtenstein, Wolfgang Nellen (Editor), Conrad Lichtenstein (Editor)
Antisense technology is a powerful procedure that permits the controlled silencing of a specific gene for investigations of mRNA and protein function. This valuable text provides proven step-by-step protocols for antisense techniques in a range of different organisms and cell culture systems. In addition it discusses the potential benefits and ...
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Adenylyl Cyclase, G Proteins, and Guanylyl Cyclase
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Colowick, Jackie D Corbin (Editor), Melvin I Simon (Editor)
This volume emphasizes methods for the assay, purification, and characterization of adenylyl cyclases, guanine nucleotide-dependent regulatory proteins (G proteins), and guanylyl cyclases. The key features include: adenylyl cyclase: determination of activity; preparation of materials useful in purification of components of hormonally responsive ...
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Adenosine and Adenine Nucleotides as Regulators of Cellular Function
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John W Phillis, Phillis W Phillis, Cook (Contributions by)
This book provides valuable information for investigators interested in the signaling and regulatory functions of adenosine and the adenine nucleotides. Topics covered in this comprehensive volume include the historical development of research on adenosine and adenosine triphosphate; various aspects of the formation, metabolism, release, transport ...
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Cyclic 3', 5'- Nucleotides: Mechanisms of Action
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Hinrich Cramer, Joachim Schultz
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Nucleotides and Regulation of Bone Cell Function
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Geoffrey Burnstock (Editor), Timothy R Arnett (Editor)
ATP's powerful impact on the heart and blood vessels was first described in 1929, but it was not until the 1970s that ATP was proposed as the 'purinergic' neurotransmitter in autonomic nerves. The door to this area of research was thrown open when receptors for ATP and its ectoenzymatic breakdown product adenosine were first cloned in the early ...
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Nucleotide Analogs: Synthesis and Biological Function
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Karl Heinz Scheit
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Chemistry and Biology of Nucleosides and Nucleotides
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Robert E Harmon
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Biophosphates and Their Analogues: Synthesis, Structure, Metabolism, and Activity: Proceedings of the 2nd International Symposium on Phosphorus Chemistry Directed Towards Biology, Odz, Poland, 8-12 September 1986
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K S Bruzik
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Nucleotide Metabolism: An Introduction
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J Frank Henderson
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Cyclic Nucleotides in Disease
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Benjamin Weiss (Editor), Physiological Society of Philadelphia
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Adenosine and Adenine Nucleotides: From Molecular Biology to Integrative Physiology
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Luiz Belardinelli
This text contains a selection of lectures given during the 5th International Symposium on Adenosine and Adenine Nucleotides, recently held in Philadelphia, Pennsylvania. It covers a wide range of subjects from molecular and cellular biology to clinical applications. Emphasis has been placed on cutting edge information derived from studies using ...
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The Pyridine Nucleotide Coenzymes
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Johannes Everse
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Nucleoside Triphosphates and Their Analogs: Chemistry, Biotechnology, and Biological Applications
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by
Morteza Vaghefi
Used extensively in cellular and molecular biology research and cytogenetic applications, nucleotide analogs are currently available for the treatment of various diseases. "Nucleoside Triphosphate and Their Analogs: Chemistry, Biotechnology, and Biological Applications" features the contributions of 18 scientists from both academia and industry in ...
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Nucleosides, Nusleotides
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Janet L Rideout
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Chemistry, Biology, and Clinical Uses of Nucleoside Analogs
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Alexander Bloch (Editor), New York Academy of Sciences
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Physicochemical Characteristics of Oligonucleotides and Polynucleotides
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Borek Janik
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