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Anatomy of Gene Regulation: A Three-Dimensional Structural Analysis
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Panagiotis A Tsonis
No longer simple line drawings on a page, molecular structures can now be viewed in full-figured glory, often in color and even with interactive possibilities. Anatomy of Gene Regulation is the first book to present the parts and processes of gene regulation at the three-dimensional level. Vivid structures of nucleic acids and their companion ...
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Molecular Diagnostics: Fundamentals, Methods and Clinical Applications
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Lela Buckingham, Maribeth L Flaws
Lela Buckingham and Maribeth Flaws have developed the most comprehensive text available for the study of molecular diagnostics in the clinical laboratory setting. "Molecular Diagnostics" will give your students the background they need to understand the principles behind diagnostic tests that use molecular techniques. With its grounding in ...
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Doctor Frank's no-aging diet
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Benjamin S. Frank, Philip Miele
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Nucleic Acids: Structures, Properties, and Functions
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Donald M Crothers, Victor A Bloomfield, Ignacio Tinoco
Providing a comprehensive account of the structures and physical chemistry properties of nucleic acids, with special emphasis on biological function, this text has been organized to meet the needs of those who have only a basic understanding of physical chemistry and molecular biology.
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Dr. Frank's No Aging Diet
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Philip Miele, Benjamin S Frank
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Capillary Electrophoresis of Nucleic Acids Volume 2: Practical Applications of Capillary Electrophoresis
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by
Keith R Mitchelson (Editor), Jing Cheng (Editor)
Capillary Electrophoresis (CE) provides researchers with the ability to separate and analyze very small amounts of DNA. CE offers important advantages over other available methods because of the speed and reproducibility of analysis. further, the high sensitivity of detection and the ability to increase sample throughput with parallel analysis has ...
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Nucleic acids in chemistry and biology
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by
Blackburn, Gait
The structure, function and reactions of nucleic acids are central to molecular biology and are crucial for the understanding of complex biological processes involved. Revised and updated Nucleic Acids in Chemistry and Biology 3rd Edition discusses in detail, both the chemistry and biology of nucleic acids and brings RNA into parity with DNA. ...
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The Biochemistry of the Nucleic Acids
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by
R L P Adams
This book provides a detailed and accessible account of all aspects of nucleic acids for students and researchers alike. The new edition of "The Biochemistry of the Nucleic Acids" has been extensively rewritten and revised to provide expanded, up-to-date coverage of topics such as nucleic acid structure and orgainisation, replication and gene ...
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Antisense Oligodeoxynucleotides and Antisense Rnanovel Pharmacological and Therapeutic Agents
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by
Benjamin Weiss (Editor)
This book is a practical, state-of-the-art treatise on antisense oligodeoxynucleotide and antisense RNA technology and the potential application of these strategies in therapeutics. Critical analyses of the specificity of the agents are featured, and the possibility of antisense oligomers acting through non-antisense mechanisms is considered. ...
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Macromolecular Crystallography with Synchrotron Radiation
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John R Helliwell
This highly illustrated monograph provides a comprehensive study of the structure and function of proteins, nucleic acids and viruses using synchrotron radiation and crystallography. Synchrotron radiation is intense, polychromatic and finely collimated, and is highly effective for probing the structure of macromolecules. This is a fast-expanding ...
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Dynamics of Proteins and Nucleic Acids
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by
J Andrew McCammon, Stephen C Harvey
This book is a self-contained introduction to the theory of atomic motion in proteins and nucleic acids. An understanding of such motion is essential because it plays a crucially important role in biological activity. The authors, both of whom are well known for their work in this field, describe in detail the major theoretical methods that are ...
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Chemistry of Nucleosides and Nucleotides
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by
LeRoy B Townsend
This third of four volumes continues the work of its well-received predecessors by providing comprehensive articles on specific lines of research. All volumes are written with medicinal chemists, organic chemists, physical chemists, and biological chemists in mind. Additionally, with the spate of recent research on the anticancer, antiviral, and ...
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Nucleic Acids, Part a: Volume 12a: Nucleic Acids
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Sidney P Colowick (Editor), Nathan O Kaplan (Editor), Lawrence Grossman (Editor)
The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential ...
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DNA: The Double Helix: Perspective and Prospective at Forty Years
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Donald A Chambers
This volume celebrates the 40th anniversary of the publication of the original papers describing the structure of DNA as a double helix, by presenting papers by many of the major participants in this biological revolution as well as by other investigators who are current leaders in the field of molecular biology. The scientific papers presented ...
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Progress in Nucleic Acid Research and Molecular Biology
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by
Kivie Moldave (Editor)
Nucleic acids are the fundamental building blocks of DNA and RNA and are found in virtually every living cell. Molecular biology is a branch of science that studies the physicochemical properties of molecules in a cell, including nucleic acids, proteins, and enzymes. Increased understanding of nucleic acids and their role in molecular biology will ...
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Peptide Nucleic Acids
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Peter E Nielsen (Editor)
Peter Eigil Nielsen has assembled a critically evaluated collection of key PNA protocols that are either already well established around the world, such as PCR-clamping and in situ hybridization, or that display promise of significant future impact. Basic methods for PNA oligomer synthesis and analysis have also been included. Written by experts ...
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Capillary Electrophoresis of Neucleic Acids Volume 1: Introduction to the Capillary Electrophoresis of Nucleic Acids
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by
Keith R Mitchelson (Editor), Jing Cheng (Editor)
Capillary Electrophoresis (CE) provides researchers with the ability to separate and analyze very small amounts of DNA. CE offers important advantages over other available methods because of the speed and reproducibility of analysis. Further, the high sensitivity of detection and the ability to increase sample throughput with parallel analysis has ...
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Circulating Nucleic Acids in Plasma and Serum IV
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by
Dr. R Swaminathan, Pro (Editor), Asif Butt (Editor), Peter Gahan (Editor)
An accurate, inexpensive, and noninvasive method for the early diagnosis of cancer has been something of a holy grail among cancer researchers, but until recently a method meeting all three criteria has been elusive. Nucleic acids were first discovered in circulation in 1948, but it was not until the 1960s and 70s that patients with autoimmune ...
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Radiation Induced Molecular Phenomena in Nucleic Acids: A Comprehensive Theoretical and Experimental Analysis
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by
Manoj K Shukla (Editor), Jerzy Leszczynski (Editor)
Comprehensive theoretical and experimental analysis of UV-radiation and low energy electron induced phenomena in nucleic acid bases (NABs) and base assemblies are presented in this book. NABs are highly photostable; the absorbed energy is dissipated in the form of ultrafast nonradiative decay. This book highlights the possible mechanisms of these ...
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Antisense Drug Technology: Principles, Strategies, and Applications
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Stanley T Crooke (Editor)
Extensively revised and updated, "Antisense Drug Technology: Principles, Strategies, and Applications, Second Edition" reflects the logarithmic progress made in the past four years of oligonucleotide-based therapies, and, in particular, antisense therapeutics and research. Interpreting lessons learned from the clinical trials of first generation ...
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Peptide Nucleic Acids: Protocols and Applications
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by
Peter E Nielsen
Peptide Nucleic Acids, Second Edition has been extensively revised, updated, and enlarged to contain many new chapters covering the most recent topics and applications in this fast-moving field. The book contains state-of-the-art protocols and applications on all aspects of peptide nucleic acids. Concepts are clearly explained with each chapter ...
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Topics in Bioorganic and Biological Chemistry
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by
Sidney M Hecht (Editor)
This work provides an overview of DNA and RNA including coverage of biosynthesis, stucture, and their functions in information storage and transmission. A review of fundamental material is presented in the first half of each chapter followed by a fairly detailed research example selected by the chapter author from current research.
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Essentials of Nucleic Acid Analysis: A Robust Approach
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Jacquie T Keer (Editor), Lyndsey Birch (Editor)
Over the last decade there has been a rapid development of molecular techniques, with an increasing range of instrumentation now available. The development of accompanying reference literature has not kept pace with technological advances and this poses significant challenges to the analyst. Essentials of Nucleic Acid Analysis sets out to guide ...
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Antisense Technology, Part A, General Methods, Methods of Delivery, and RNA Studies
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by
M Ian Phillips (Editor), Abelson
Antisense technology is the ability to manipulate gene expression within mammalian cells providing powerful experimental approaches for the study of gene function and gene regulation. For example, methods that inhibit gene expression permit studies which probe the normal function of a specific product within a cell. Such methodology can be used in ...
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Nucleic Acid Protocols Handbook
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by
Ralph Rapley (Editor)
This is a comprehensive treasury of all the key molecular biology methods - ranging from DNA extraction to gene localization in situ - needed to function effectively in the modern laboratory. Each of the 120 highly successful techniques follows the format of the much acclaimed "Methods in Molecular Biology" series, providing an introduction to the ...
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