This updated and expanded tutorial guide to molecular diagnostic techniques takes advantage of many new molecular technologies to include both improved traditional methods and totally new methods, some not yet in routine use. The authors offer cutting-edge molecular diagnostics for genetic disease, human cancers, infectious diseases, and identity ...
Lela Buckingham and Maribeth Flaws have developed the most comprehensive text available for the study of molecular diagnostics in the clinical laboratory setting. "Molecular Diagnostics" will give your students the background they need to understand the principles behind diagnostic tests that use molecular techniques. With its grounding in ...
This advanced level textbook provides a comprehensive overview of recent developments in the area of molecular based diagnostics (including nucleic acids, biosensors and immunoessays) of disease markers. It also covers the impact of techniques such as in vitro nucleic acid amplifications (e.g. PCR) and other amplification methods, as well as gene ...
Pathology is an inherently subjective discipline, and therefore is often referred to as both an art and a science. Over the years, laboratory physicians have implemented special tissue stains and molecular techniques to limit subjectivity in the discipline. Beginning in the late 19th century, histochemical stains were developed to assess ...
John Walker and Ralph Rapley have collected a wide-ranging group of molecular and biochemical techniques that are the most frequently used in medical and clinical research, especially diagnostics. The authors - well-established investigators who run their own research programs and use the methods on a regular basis - outline the practical ...
Prominent researchers and clinicians describe in detail all the latest laboratory techniques currently used to define the molecular genetic basis for congenital malformations of the heart, cardiomyopathies, cardiac tumors, and arrythmias in human patients. In particular, the methods can be used to identify in clinical samples those genetic ...
This is a collection of readily reproducible classic and emerging molecular methods for the laboratory isolation and identification of the pathogens, viruses, and parasites that cause food-borne disease. Among the pathogens covered are specific bacteria, including Salmonella spp, Campylobacter spp., Listeria spp., and Bacillus spp.; viruses, ...
This is a collection of basic and advanced molecular methods that reveal those markers essential for more accurate diagnoses of specific diseases, and in developing new treatment strategies. The techniques range from in vitro methods to in vivo models of prostate cancer, and include new methods for the accurate diagnosis of prostate cancer, ...
Leading physician scientists and noted researchers describe step-by-step techniques for lung cancer diagnosis based on the molecular analysis of clinical samples. These experts review currently accepted treatments and outline a variety of novel therapies, including those based on gene therapy, immunotherapy, and chemoprevention, and show how these ...
To date, molecular biology techniques have been introduced to all fields of modern biomedical research and are now finding their way into diagnosis and even therapy. This laboratory manual is designed for researchers who have started or are planning to use molecular biology techniques and need reliable protocols for their laboratory work. It is ...
This second edition of a classic laboratory manual describes cutting-edge methods for the protein-based diagnosis of infectious diseases. Explaining the latest developments in genomics, proteomics, bioinformatics, biosensors, high-throughput devices, and recombinant technology, the authors apply these new methodologies successfully to the ...
Expert laboratory and clinical researchers from around the world review how to design and evaluate studies of tumor markers and examine their use in breast cancer patients. The authors cover both the major advances in sophisticated molecular methods and the state-of-the-art in conventional prognostic and predictive indicators. Among the topics ...
Over the last three decades, knowledge on the molecular biology of human cancers has vastly expanded. A host of genes and proteins involved in cancer development and progression have been defined and many mechanisms at the molecular, cellular and even tissue level have been, at least partly, elucidated. Insights have also been gained into the ...
Written by world-renowned experts, this book addresses immunological and molecular methodologies of diagnosis as well as clinical aspects of diseases. The book discusses DNA and RNA amplification methods, explains ELISA approaches, and introduces rapid diagnosis techniques, biosensors, and flow cytometry. The book examines bacterial and parasitic ...
Busy clinicians and health practitioners recognize the importance of speedy detection of pathogens to impede the further spread of infection, and to ensure their patients' rapid and complete recovery. This reader-friendly reference is a unique collection of the newest and most effective diagnostic techniques currently in use in clinical and ...
Second Edition features the latest tools for uncovering the genetic basis of human disease. The Second Edition of this landmark publication brings together a team of leading experts in the field to thoroughly update the publication. Readers will discover the tremendous advances made in human genetics in the seven years that have elapsed since the ...
The aim of "Single Cell Diagnostics: Methods and Protocols" is for all readers to extend their knowledge and expertise in analysis of single cells. The book starts with laser assisted cell collection, non-invasive assessment of single cells and moves through the techniques of standard fluorescence in situ hybridization and polymerase chain ...
Automation is facilitating incredible breakthroughs in everything from healthcare, pharmacology, and biotechnology to nanotechnology and genomics. Automation developers, scientists, and technicians need an increasingly sophisticated understanding of both the biological sciences and the engineering involved, and this comprehensive resource is the ...
provides complete coverage of the principles and applications of molecular microbiology as they pertain to infectious diseases; summarizes the basic scientific theory underlying molecular diagnostics; reviews proven applications of molecular diagnostic techniques for the diagnosis of infectious diseases.
High-profile laboratory scientists and basic cancer researchers review those recent and future clinical laboratory tests that can help in the early detection, evaluation, and prediction of human tumors, and so permit more informed therapeutic decisions. Emphasizing the importance of molecular and genetic RNA/DNA tests that can detect persons at ...
This volume in the "Foundations in Diagnostic Pathology Series" packs today's most essential cell and tissue base molecular pathology into a compact, high-yield format! It focuses on the state of the art in practical validated molecular diagnostics as applied across the fields of surgical pathology and cytology. With an emphasis on current, ...
This completely revised and updated second edition to integrates the many new technologies and insights now available for the diagnosis of genetic diseases. The authors use such methodologies as PCR optimization dosage analysis, mutation scanning, and quantitative fluorescent PCR for aneuploidy analysis, Neurofibromatosis type 1, and Duchenne ...
There has been a rapid introduction of nucleic acid-based analysis techniques into diagnostic labs. This book presents the theory and approaches of molecular methods to the diagnosis of genetic diseases, cancer, and viral, bacterial and parasitic infections. The theory of nucleic acid structure and function is summarized to explain hybridization, ...
Facilitating efforts to prevent melanoma progression, this up-to-date reference presents the most recent advances in the pathology, molecular biology, and therapy of melanoma in early, high-risk, and advanced stages. Discusses growth factors, cytokines, receptors, oncogenes, tumor suppressor genes, adhesion molecules, and proteases in melanoma ...
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