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Magic Molecules: How Drugs Work
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Dr. Susan Aldridge
All of us are drug users, in the broadest sense of the word. Drugs can be medicines, they can be used for pleasure, and they can also be used to protect our long-term health. It is important that we are well informed about the drugs we use - how they work, their benefits and their risks. This book is a unique guide for the general science reader ...
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Psychopharmacology of Antidepressants
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Stephen M Stahl, Stahl M Stahl
An innovative, easily-accessible introduction to the subject for both clinicians and trainees. Illustrated throughout in colour, this handbook offers an invaluable visual lesson detailing data and information on all classes of antidepressants currently available.
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Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy 2
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Pinedo, Schornagel
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Tissue-Specific Estrogen Action: Novel Mechanisms, Novel Ligands, Novel Therapies
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by
Kenneth S Korach
The multiple actions of estrogens on different cell types have not only intrigued endocrinology researchers but also inspired the development of selective estrogen receptor modulators, or SERMs, that modulate estrogen signaling in a cell type-specific manner. Current molecular understanding of estrogen action has greatly profited from advances in ...
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Calcium Channel Pharmacology
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Stefan I McDonough (Editor)
This volume reviews the current ability, future prospects, and physiological and medical significance of being able to distinguish pharmacologically among different calcium channel subtypes. Chapters are organized around broad concepts addressing the state of the field that naturally cover the pharmacology of each different calcium channel. ...
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Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy
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Howell
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Biochemical Sites of Insecticide Action and Resistance
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by
Isaac Ishaaya (Editor)
The authors of this book report up-to-date methodologies relating to isolation, identification and use of various enzymes and receptor systems that serve as targets for insecticide action or as sites for resistance development. Thus, this book serves as an indispensable tool for scientists in academia and industry research, investigating or ...
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Modes of Action of Gnrh and Gnrh Analogs
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by
William F Jr Crowley (Editor), P Michael Conn, Ph.D. (Editor)
The goal of the "Serono Symposia," USA Series is to promote scientific and clinical education for scientists, physicians, nurses, and pharmacists. Each high-quality publication presents the research of outstanding professionals in the field. The newest volume in the series is Modes of Action of GnRH and GnRH Analogs. Over the past twenty years, ...
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Proteases in Tissue Remodelling of Lung and Heart
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Uwe Lendeckel (Editor), Nigel M Hooper (Editor)
"Proteases in Tissue Remodelling of Lung and Heart" is unique for its comprehensive presentation of protease function in lung and heart under both physiological conditions and major diseases manifesting in these two organs. The individual chapters have been written by leaders in the field who paid much attention to outline in great detail the role ...
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Studies of Narcosis
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by
Charles Ernest Overton, Robert L. Lipnick
This volume is an English translation of Overton's monograph on structure-activity relationships regarding anaesthetic action and toxicity. This book has been cited widely by scientists studying the correlation of biological activity with partition coefficients and the mechanism of anaesthesia. Although the original monograph was published in 1901 ...
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Enzyme Systems That Metabolise Drugs and Other Xenobiotics
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by
Costas Ioannides (Editor)
This definitive reference work describes in detail the enzyme systems that participate in the metabolism of xenobiotics, particularly medicinal drugs. Each chapter focuses on a specific enzyme system, emphasising its role in the activation and detoxication of chemicals. Aspects discussed critically include: enzyme function in the metabolism and ...
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Topics in Vaccine Adjuvant Research
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by
Dale R Spriggs (Editor), Wayne C Koff (Editor)
"Topics in Vaccine Adjuvant Research" provides a concise, focused review of the immunological basis of adjuvant activity. The first section of the book contains several chapters that discuss key issues in cellular immunology, such as antigen processing and presentation, cytokine regulation of immune responses, and mucosal immunology. The second ...
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Hematopoietic Growth Factors in Oncology
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by
George Morstyn (Editor), Maryann Foote (Editor), Graham J Lieschke (Editor)
Leading oncologists, hematologists, and nephrologists comprehensively review the role of HGFs in clinical practice, explain the molecular basis of their effects, and consider potential future developments. The authors focus on the use of HGFs in oncology, describing their cutting-edge application to patients with lung cancer, Hodgkin's and ...
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Insecticides Design Using Advanced Technologies
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by
Isaac Ishaaya
In the past, insecticide development has been guided mostly by chemo-rational and bio-rational design based on understanding of the physiology and ecology of insects and crops. A limitation in each new class of compounds is the evolution of resistance in populations of key pests, which ultimately leads to control failures. This phenomenon and the ...
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Serotonin: Molecular Biology, Receptors and Functional Effects
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J Fozard, P Saxena
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Insecticides with Novel Modes of Action
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by
Isaac Ishaaya (Editor), Danny Degheele (Editor)
This book conveys a wealth of information on pesticide chemistry, biochemical modes of action, biological activity, and theory of pesticide application for management programs. Emphasis is placed on novel biological insecticides which block certain stages in the development of pest insects. Special attention is given to insecticides with selective ...
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Arachidonate Remodeling and Inflammation
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Robert L Wykle (Editor), Alfred N Fonteh (Editor)
Arachidonic acid (AA) and other 20 or 22-carbon polyunsaturated fatty acids (PUFAs) are precursors of lipid mediators of inflammation known as eicosanoids. These mediators are critical in disease processes and in regulating normal cell function. Remodeling is important in maintaining homeostasis and in regulating cell function by dictating how ...
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Gnrh Analogues: The State of the Art at the Millennium
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by
Bruno Lunenfeld (Editor)
This is the most up-to-date clinical reference available on the use of gonadotropin-releasing hormone (GnRH) analogs in assisted reproductive technology (ART) and in medical treatment. In ten chapters contributed by world-class experts, the book describes the mechanisms of action of GnRH and the future of GnRH analogs, including safety issues, ...
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Free Radicals in the Brain: Aging, Neurological, and Mental Disorders
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by
Lester Packer
There is an increasing body of literature suggesting that at some stage during the development of most human diseases free radicals may be involved, and therefore retarded by antioxidants. Although in some cases this evidence is only circumstantial, it is becoming overwhelming. In particular, certain brain disorders and ageing itself appear to ...
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Clinical Applications of the Interferons
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by
Stuart-Harris, Penny
This text aims to provide a comprehensive body of information concerning the clinical usage of interferons. The book covers the history of the development and introduction of the interferons, as well as chapters on their mechanism of action and a look to the future. There are also sections on the use of interferons in viral diseases, in ...
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Mechanism of Action of Antimicrobial and Antitumor Agents
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J. W. Corcoran (Editor), F. E. Hahn (Editor)
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Metabolism of brain peptides
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by
O'Cuinn
Metabolism of Brain Peptides discusses neuropeptide metabolism in light of recent research. It describes the processing mechanisms in the production of biologically active peptides. It details distribution of the variety of neuropeptides in the brain and comprehensively reviews the effects of these neuropeptides on behavioral and physiological ...
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Acetylcholine: An Approach to the Molecular Mechanism of Action,
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M Ia Mikhel'son
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Mechanisms and control of emesis : a satellite symposium of the European Neuroscience Association : proceedings of an international meeting held in Marseille (France), 4-7 September 1992: "New Vistas on Mechanisms and Control of Emesis" = Mécanismes et...
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by
Armand L. Bianchi
This work features the text in French and English. This work contains the Satellite Symposium of the European Neuroscience Association's proceedings of an International Meeting Held in Marseille (France), 4-7 September, 1992 on New Vistas on Mechanisms and Control of Emesis.
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Adrenal in Toxicology: Target Organ and Modulator of Toxicity
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by
Harvey W Harvey, Philip W Harvey (Editor)
The adrenal gland is vitally important to health and secretes hormones that control many bodily processes ranging from normal metabolism to the response to stressful circumstances. The corticosteroid hormones are the basis for anti-inflammatory medicines and are very widely prescribed. Changes in the function of the adrenal gland, either naturally ...
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