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Cellular and Molecular Immunology
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Abul K Abbas
The book provides a synthesis and critical analysis of advances in the field of cellular and molecular immunology, and aims to help the reader review the respective literature from the proper perspective. It offers material on the functional anatomy of immune responses, including regional immunity such as the cutaneous and mucosal immune systems. ...
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Cellular and Molecular Immunology: With Student Consult Online Access
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Abul K Abbas, Andrew H Lichtman, Shiv Pillai
The 6th Edition of this well loved title continues the tradition of giving you an accessible, engaging, and current introduction to this essential subject. The authors help you to understand the principles of basic and applied immunology in a concise, straightforward manner, while incorporating the most up-to-date information. Excellent ...
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T-Cell Dependent and Independent B-Cell Activation
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E. Charles Snow (Editor)
This book provides an analysis of the current subdisciplines comprising the study of humoral immune response. The first chapter presents a detailed discussion regarding the experimental and conceptual studies conducted prior to the mid-1970s that have served as a valuable research framework for investigators interested in the process by which B ...
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Killer Lymphocytes
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by
Gideon Berke, William R Clark
We have known about the existence of killer lymphocytes since 1960, when they were discovered in connection with transplant rejection in vivo. Since then, we have uncovered at least five subsets of lymphocytes that can kill other cells in vitro, establishing the study of cell-mediated cytotoxicity (CMC) as a major field of immunological inquiry. ...
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Flow Cytometry in Clinical Diagnosis
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David F. Keren
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Lymphocytes: A Practical Approach
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Sarah L Rowland-Jones (Editor), Andrew J McMichael (Editor)
Cellular immunology is a rapidly moving field in which recent advances have made significant contributions to our understanding of the immune response to infection and malignancy. These in turn, have given rise to new therapeutic opportunities in areas such as vaccines and immunotheraphy. Many investigators have been discourages by the ...
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B1 Lymphocytes in B Cell Neoplasia: 16th Workshop on the Mechanisms of B Cell Neoplasia 1999
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Michael Potter, Fritz Melchers
An exciting trend in B-cell biology is the growing recognition of the importance of natural antibodies to immune defence. B-1 cells are a substantial source of natural antibodies. This workshop brought together many of the leading people in this field to discuss the current status of B-1 cells, their developmental origin and their function. This ...
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Immunological Tolerance: Methods and Protocols
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Paul J Fairchild (Editor)
"Immunological Tolerance: Methods and Protocols" is a comprehensive guide to the techniques currently used for culturing and characterising the cell types responsible for imposing self-tolerance and the experimental models employed to study their function both in vitro and in vivo.
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Mechanisms of Lymphocyte Activation and Immune Regulation VI
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Sudhir Gupta (Editor), J John Cohen (Editor)
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An Imagined World: A Story of Scientific Discovery
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June Goodfield
Brings to life the human and creative nature of scientific discovery to the nonscientist.
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T Lymphocytes Subpopulations in Immunotoxicology
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Maryjane K Selgrade (Editor), Ian Kimber (Editor), Mary Jane Selgrade (Editor)
T Lymphocyte Subpopulations in Immunotoxicology Edited by Ian Kimber ZENECA Pharmaceuticals, Central Toxicology Laboratory, Macclesfield, Cheshire, UK and Mary Jane K. Selgrade US Environmental Protection Agency, National Health and Environmental Effects Research Laboratory, NC, USA Immunotoxicology is a diverse discipline that embraces the ...
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Lymphocyte Signal Transduction
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by
Constantine Tsoukas (Editor), Ed Tsoukas Constantine
Signal transduction through leukocyte receptors involves a variety of signaling molecules including kinases, phosphatases, adaptor proteins, small GTPases GTP exchange factors, membrane phospholipids as well as others. These signal transducers, regulated by inter- and intra-molecular interactions, as well as by various post-translational ...
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T Cell Protocols: Development and Activation
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Kelly P Kearse (Editor)
Kelly P. Kearse and a panel of laboratory experts describe the step-by-step execution of a wide variety of basic and specialized techniques for the study of T cell developmental biology and of their subsequent activation. Readily reproducible, the techniques are explained concisely, but in such detail that they are suitable for both the novice and ...
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Limiting Dilution Analysis of Cells of the Immune System
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Ivan Lefkovits, Herman Waldmann, P Rovensky
This edition is a treatise on the rationale of limiting dilution analysis (LDA). LDA has evolved from its previous role as a basic research laboratory tool in virology and immunology to one pertaining to many different research disciplines and to clinical applications. New methodologies (such as PCR, confocal microscopy, in situ hybridization) ...
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Cytotoxic Cells: Recognition, Effector Function, Generation, and Methods
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by
Michail Sitkovsky, P a Henkart (Editor)
This collection of papers from researchers of cytotoxic cells provides a state-of-the-art review of this field. Special chapters cover the mechanisms of lethal hit delivery and immuno-pharmacological manipulations of cytotoxic cells.
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B Cell Protocols
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by
Hua Gu, PhD, Klaus Rajewsky, Hau Gu
This is a diverse collection of protocols ranging from the latest inventions and applications to some classic, but still frequently used, methods for studying B-lymphocyte development and function in higher animals. These readily reproducible protocols follow the successful "Methods in Molecular Biology" series format, each one offering step-by ...
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The Lymphocyte: Structure and Function, Second Edition
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John Marchalonis
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Natural Killer T-Cells: Roles, Interactions, and Interventions
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Nathan V Fournier
Natural killer T (NKT) cells are a heterogeneous group of T cells that share properties of both T cells and natural killer (NK) cells. Many of these cells recognize the non-polymorphic CD1d molecule, an antigen-presenting molecule that binds self and foreign lipids and glycolipids. Upon activation, NK T cells are able to produce large quantities ...
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Generation and Effector Functions of Regulatory Lymphocytes
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by
Novartis Foundation Symposium (Creator)
Over the last several years, immunologists have re-discovered the importance of regulatory lymphocytes, formerly termed 'suppressor cells'. Many recent reports have documented their existence, effector functions and potential therapeutic benefits in autoimmunity and transplantation. However, even though modern techniques have allowed us to get a ...
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Superantigens #7 (93)
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Brigitte T Huber, Brigitte T Huber (Editor), Ed Palmer (Editor)
Superantigens are microbial products that defy the conventional notion of lymphocyte activation to produce an unusually vigorous, genetically unrestricted response among many subsets of antigen-specific T cells. Bacterial toxins and certain viral gene products behave as superantigens, deleting T cells in vivo and stimulating their proliferation in ...
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Lymphocyte Trafficking in Health and Disease
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Raffaele Badolato (Editor), Silvano Sozzani (Editor)
Since the discovery of chemokines and of chemokine receptors it has become evident that expression of chemokines at the site of inflammation may regulate the composition of cellular infiltrate, thereby directing the type of immune response. Recently, the molecular characterization of inherited disorders of immune system, (e.g., Wiskott-Aldrich ...
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T-cell-directed immunointervention
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by
Bach
Autoimmunity, the phenomenon by which the body's immune system attacks itself instead of invading organisms, is a factor in a wide range of currently
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Ligands, Receptors, and Signal Transduction in Regulation of Lymphocyte Function
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John C Cambier (Editor)
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Handbook of Elispot: Methods and Protocols
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by
Alexander E Kalyuzhny (Editor)
In this first book dedicated entirely to the ELISPOT, a critical enzyme-linked immunospot assay used widely in biomedical research, recognized experts with first-hand experience detail how to design, perform, and analyze these assays. The readily reproducible techniques they provide cover a wide variety of topics, including the use of membrane ...
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Antigens, Lymphoid Cells, and the Immune Response
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by
G J V Nossal
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