This collection of papers from researchers of cytotoxic cells provides a state-of-the-art review of this field. Special chapters cover the mechanisms of lethal hit delivery and immuno-pharmacological manipulations of cytotoxic cells.
This text examines in vitro cytotoxicology, which offers new methodologies to toxicity testing. This discipline of modern toxicology is gaining increasing acceptance as a viable alternative to traditional testing methods. The text discusses the application of in vitro cytotoxicology to toxicity testing and human risk assessment, and analyzes the ...
Covers the molecular basis of superoxide generation by phagocytes, the major pathways of oxidative injury, events at the leukocyte superoxide generator/target interface, regulatory events that feed back to modulate leukocyte superoxide production, and the role of leukocyte oxidants in disease.
This volume synthesizes recent groundbreaking advances in our knowledge of the molecular mechanisms, biological roles, and medical applications of cytotoxic lymphocytes. Leading investigators examine current concepts on the recognition of antigen by T-cell receptors; the molecules mediating target recognition by natural killer cells; the ...
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