Several international symposia on chronic inflammatory bowel disease in the 1990s have contributed to our understanding of the pathophysiology and treatment of this condition. Molecular biology and analytical techniques have continuously improved our knowledge of mucosal immunology and of inflammatory reactions. Progress in this field is very ...
Colorectal cancer is one of the most common causes of tumour-associated death in Western countries, and its incidence has been increasing in recent decades. The most important determinant for the course of the disease is tumour stage at the time of diagnosis. The detection of molecular changes in tumour tissue and in benign adenomatous polyps has ...
Portal hypertension is causally related to major complications of chronic liver disease like upper GI tract bleeding, ascites formation, portosystemic encephalopathy and bacterial infections. Recent approaches have increased knowledge of the underlying pathobiological events of these complications. Accordingly, promising treatment modalities have ...
Zinc has an important role in human physiology due to its involvement in numerous enzymatic reactions and its other functions as part of hormones and structural proteins. As a consequence a wide variety of symptoms may occur in different states of zinc deficiency. Several diseases of the digestive tract can lead to zinc deficiency and consequently ...
Inflammatory bowel diseases are still a challenging problem in today's gastroenterology. Although their aetiology is still not understood, steady progress has been made recently in the understanding of their pathogenesis, due to the application of innovative molecular and cellular biological methods. Knowledge of the immunology of the gut and the ...
Although chronic inflammatory bowel diseases (IBD) have been described for more than a century and despite the progress made in the last decade, their etiology and pathogenesis are still not completely understood. This publication presents the state-of-the-art regarding etiology, pathogenesis, diagnosis, clinical presentation and treatment of IBD. ...
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