Cytochromes P450: Metabolic and Toxicological Aspects examines cytochrome P450 proteins and their role in toxicity/carcinogenicity and the metabolism of foreign chemicals. Studying the function of these proteins enables us to:oPredict the pathways and outcome of chemical metabolism to rationalize species, sex, and age differences in ...
During half a century, cytochrome P450 in its original uniqueness as an optically "wrong" cytochrome has attracted many investigators, who have contributed to the unveiling of a bewildering multiplicity of biologically important functions of the, by now very large, superfamily of cytochrome P 450 enzymes. With its discovery in 1958 and with the ...
This definitive reference work describes in detail the enzyme systems that participate in the metabolism of xenobiotics, particularly medicinal drugs. Each chapter focuses on a specific enzyme system, emphasising its role in the activation and detoxication of chemicals. Aspects discussed critically include: enzyme function in the metabolism and ...
Current Toxicology Series Series Editors Diana Anderson BIBRA Toxicology International, Surrey, UK Michael D Waters Consultant, Chapel Hill, NC, USA Timothy C Marrs Department of Health, London, UK Nutrition and Chemical Toxicity Edited by Costas Ioannides, University of Surrey, Guildford, UK An enormous amount of research is currently devoted to ...
The second title in a three-volume work reviewing the inter-relationships between drugs, diet and disease. Developments in the field of diabeties are reviewed, providing a clear picture of the roles played by drugs and diet in the aetiology, pathogenesis and management of the disease.
This is the first title in a three-volume work reviewing the interrelationships between drugs, diet and cancer. It is a multidisciplinary book which reflects current developments. This work is intended for: researchers and developers in the pharmaceutical industry worldwide, as well as the food industry; medical and nutritional clinicians; ...
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