The cinema of Preston Sturges maintains an enduring presence in the small canon of films that enjoy critical acclaim, scholarly attention, and popular admiration. Following the reception of "Five Screenplays" by Preston Sturges, this text provides "Four More". This volume contains three scripts widely regarded as among the film-maker's best: "The ...
This book reviews current understanding of the biological roles of extracellular molecular chaperones. It provides an overview of the structure and function of molecular chaperones, their role in the cellular response to stress and their disposition within the cell. It also questions the basic paradigm of molecular chaperone biology - that these ...
This book provides an in-depth analysis of the mechanisms and biological consequences of genome rearrangements in bacteria. Genome rearrangements are a result of the actions of discrete genetic elements such as conjugative transposons, plasmids, phage, and non conjugative transposons. Bacteria also contain systems to mediate genetic rearrangements ...
In the last ten years, substantial progress has been made in identifying why some people are particularly susceptible to specific infectious diseases. Extensive evidence has now accumulated that host genes are important determinants of the outcome of infection for many common pathogens. This book summarises the advances that have been made in ...
Hormonal carcinogenesis is an important and controversial area of research. In addition to accelerating existing cancers, can hormones play the role of primary carcinogens? And how do genetic factors influence hormone-related cancer risk? This work addresses these questions. During the last few decades of the 20th century, cancer research focused ...
Our survival as multicellular organisms requires the constant surveillance of our internal and external (mucosal) environments by the multifarious elements of the innate and acquired systems of immunity. The objective of this surveillance, expensive as it is to the organisms, is to recognise and kill invading microorganisms. Over the past fifty ...
Cytokines are peptide or protein cell-to-cell signaling molecules that play vital roles in normal cell and tissue homeostasis, as well as in responses to infectious agents. Because of their importance in virtually all forms of pathology, the pharmaceutical industry is devoting great effort to develop methods for the control of cytokine synthesis ...
This book is concerned with the underlying science and design of laser materials. It emphasizes the principles of crystal-field engineering and discusses the basic physical concepts that determine laser gain and nonlinear frequency conversion in optical crystals. A concise review of the essential underlying science is presented, and the predictive ...
Antibiotic resistance and our consequent inability to treat many bacterial infections had fuelled an urgent need to understand the means by which bacteria cause disease. This has lead to a renaissance in research into bacterial disease mechanisms and the birth of a new discipline - cellular microbiology. The fruits of such research and how they ...
Salmonella enterica encompasses a diverse range of bacteria that cause a spectrum of diseases in many hosts. Advancements in prevention and treatment of S. enterica infections have at times been hampered by compartmentalization of research efforts and lack of multidisciplinary approaches. This book attempts to cover a diverse range of topics ...
Spanning the 1950s to the 1990s, this volume is a collaborative effort by past and present editors of "Film Quarterly" to celebrate and illuminate the medium that has prompted so much thought and exchange during the journal's lifetime.
Bacterial toxins that act inside cells interact very specifically with key components of the cell and some even manipulate the cell in subtle ways for their own purposes. These potent toxins, described in this book, will be of interest to both microbiologists and cell biologists. Some of these toxins are conventional multidomain toxins that are ...
This book concerns the intimate association between bacteria and host cells. Many bacterial pathogens are able to invade and survive within cells at mucosal membranes. Remarkably, the bacteria themselves orchestrate this process through the exploitation of host cellular signal transduction pathways. Intracellular invasion can lead to disruption of ...
Cellular Microbiology is a new area of microbiology research, bridging the gap between the disciplines of microbiology and cell biology. It is the study of the interaction between cells and microbes, especially mammalian or plant cells and bacteria. Cellular Microbiology is an advanced textbook for students of microbiology and medical ...
This book is about the adhesion of bacteria to their human hosts. Although adhesion is essential for maintaining members of the normal microflora in/on their host, it is also the crucial first stage in any infectious disease. It is important, therefore, to fully understand the mechanisms underlying bacterial adhesion so that we may be able to ...
An emerging theme in molecular and cellular microbiology has been the ability of many pathogens to usurp the host cell and eventually colonize the host. This interaction between bacteria and host is not unidirectional - both pathogens and host cells engage in a signalling cross-talk. Research focused on this cross-talk and discussed in this volume ...
This book provides up-to-date information on the crucial interaction of pathogenic bacteria and professional phagocytes, the host cells whose purpose is to ingest, kill, and digest bacteria in defense against infection. The introductory chapters focus on the receptors used by professional phagocytes to recognize and phagocytose bacteria, and the ...
This book provides a systems-based approach to periodontology and offers a scientific roadmap of the interactions which can lead to periodontal disease.
The new work centres on the Memoirs of Daniel Paul Schreber, perhaps the most written about of mental patients, as well as one of the most articulate. The Memoirs formed the basis of Freuds theory of paranoia, the interpretation of which was a primary cause of the split between Jung and Freud, was the basis of Bleulers definition of schizophrenia ...
Ninety percent of the cells in the human body are bacteria, and humans may be host to many thousands of different species of bacteria. These striking statistics are part of a new paradigm in microbiology in which bacteria are no longer viewed as disease-causing killers but more as lifelong partners which are often essential for the survival of ...
All cellular life-forms can exist in replicating and non-replicating states. Organisms replicate only when the conditions are beneficial, and when not replicating they concentrate on survival of these environmental stresses. Many bacteria, harmful to humans, survive the period of infection in a low growth state. This book addresses the basic ...
Cytokines have become established as key mediators of the signs and symptoms of inflammatory diseases such as arthritis and dermatitis. This work reviews advances in the development of new anti-inflammatory drugs. It addresses different therapeutic intervention possibilities for new drugs.
Bacteria are best known for causing disease, but the fact that every human contains ten times as many bacteria as he or she does human cells suggests that the interactions between bacteria and higher organisms must be complex and under careful control. This volume brings together the current literature on bacterial virulence and on cytokines to ...
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