Along with Francis Crick, James Watson was the discoverer of the double helix structure of the DNA molecule, realising both how it was able to reproduce itself and how, through its immense variety, it was able to pass on genetic instructions from one generation to the next. Their discovery paved the way for fifty years of explosive scientific ...Read MoreAlong with Francis Crick, James Watson was the discoverer of the double helix structure of the DNA molecule, realising both how it was able to reproduce itself and how, through its immense variety, it was able to pass on genetic instructions from one generation to the next. Their discovery paved the way for fifty years of explosive scientific achievement, of extraordinary importance both in strictly scientific terms and for its technological and social significance. From Dolly the sheep to GM foods to designer babies, science-related newspaper headlines have been dominated by the implications of their work. In this book, written to tie-in with a major PBS series in the US, Watson tells the story of this research and its impact on the world in which we live, from its beginnings to the present.Read Less
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A wonderful reintroduction to the world of genomics since the frontier days of "The Double Helix"! Processes and terms are interspersed with anecdotes about the researchers and their failures as well as successes. Politics and ethics mingle with pure science. A comprehensive index allows for easy review of terms.
May 24, 2007
For anyone who wants to know more of the journey to finding DNA, how it works in all of us and onwards to Genetic Engineering of foods and possible ways to cure diseases in the future.
Publishers Weekly, 2003-03-03 Who better than James Watson to lead a guided tour of DNA? When he and his English colleague, Francis Crick, discovered the double helix structure of the DNA molecule in 1953, little could they imagine that a mere 50 years later scientists would be putting the finishing touches on a map of the human genome. In this magisterial work, Watson, who won the Nobel Prize with Crick for their discovery, guides readers through the startling and rapid advances in genetic technology and what these advances will mean for our lives. Watson covers all aspects of the genome, from the layout of four simple bases on the DNA molecule through their complex construction into genes, then to the mechanisms whereby proteins produced by genes create our uniquely human characteristics-as well as the genetic mutations that can cause illnesses or inherited diseases like Duchenne muscular dystrophy and Huntington's disease. Watson may have mellowed a little over the years since he displayed his youthful brashness in The Double Helix, but he still isn't shy about taking on controversial subjects. He criticizes biotech corporations for patenting genes, making diagnostic medical procedures horribly expensive and damping further basic research. He notes that while China and other countries with large populations to feed have eagerly grasped the potential of genetically modified foodstuffs, America squandered $100 million on a recall of taco shells and the genetically modified corn used in them. He pleads passionately for the refinement and widespread use of prenatal genetic testing. Watson will probably provoke the most controversy with his criticism of scientists, corporations and government funding sources for their avoidance of important areas of research-notably the genetics of skin coloration-for political reasons. Every reader who wants to understand their own medical future will want to read this book. 100 color and b&w illus. 150,000 first printing; BOMC and History Book Club selection. (Apr. 7) FYI: A five-part PBS series on DNA featuring Watson will air later this year. (c) Copyright PWxyz, LLC. All rights reserved
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