Chromosomal defects are one of the most common causes of genetic disorders and are responsible for a large proportion of miscarriages. As a result, more and more parents are becoming interested in genetic counseling in order to learn about the risks of reproductive failure, or to understand why they had a child with a particular defect, whether it ...
Chromosomal defects are one of the most common causes of genetic disorders and are responsible for a large proportion of miscarriages. As a result, more and more parents are becoming interested in genetic counseling in order to learn about the risks of reproductive failure, or to understand why they had a child with a particular defect, whether it will happen again, and what might be done to prevent it. This book addresses these and other questions concerning chromosome abnormalities. Although the book is written primarily for genetic counselors and laboratory workers in cytogenetics, it will be of interest to all physicians concerned with genetic counseling. Each chapter discusses a different type of defect, such as translocations, duplications, insertions, deletions, and non-disjunction. The basic biological theory underlying the problem is discussed and in-depth information is provided on the reproductive risks of chromosomally abnormal individuals and of normal parents who have a child with a chromosome abnormality. The book will help concerned parents determine an appropriate course of action, including prenatal diagnosis, and help counselors to communicate the information necessary for responsible decision-making.
New in new dust jacket. Chromosome abnormalities have been known for over 50 years, though the methods of analysis have become increasing more sophisticated and precise. Surprisingly, the questions that parents and families raise in genetic counseling have changed little over that period. Questions like, "Why did an abnormality happen? Why did it cause the problems we see in our child? Would it happen again in a future child? How could we avoid it happening again? " are common concerns for families. This new edition of Chromosome Abnormalities and Genetic Counseling deals with these universal questions, and in the context of the recent developments in molecular cytogenetic analysis, but retaining always the major focus on the needs of the families in which these conditions occur. Thoroughly updated once again, this richly-illustrated text combines basic concepts of chromosomal analysis with practical applications of recent advances in molecular cytogentics. The book will give counselors the information that will enable them to help concerned parents accommodate and adapt to their particular chromosomal challenges and to determine what may be, for them, the best course of action.
The book is definitely worth buying. It's a great reference with tons of information and guidlines on what to do with different chromosomal abnormalities and what to expect with regards to the recurrence risk. I love it! Some times it can be so detailed that it would become boring a little bit
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